JACKSONVILLE, Fla. -- The Jaguars have ruled nose tackle DaVon Hamilton and safety Eric Murray out for the remainder of the season after both players suffered season-ending injuries in Sunday's win over the Indianapolis Colts, coach Liam Coen said Monday evening.
Both players will be placed on injured reserve in the next few days, Coen added.
Hamilton suffered a torn quadriceps muscle in the second quarter of the Jaguars' 42-7 victory at EverBank Stadium. Murray injured his elbow on the game's opening kickoff. Both are key parts of a Jacksonville defense that leads the NFL in rush defense, allowing a league-low 77.4 rushing yards per game, and second in scoring defense at just 15.9 points per game.
Hamilton was surrounded by teammates while he was down on the field and was eventually taken to the locker room via a cart. He will undergo further tests today. Coen and multiple players have said Hamilton has been the key to the Jaguars' top-ranked run defense. He has 16 tackles, a forced fumble, a fumble recovery and a half sack over seven games this season.
"There's not many better humans, better competitors, team guys," Coen said of Hamilton after Sunday's game. "You should have saw D-Ham this week in practice. His leadership [with the] defensive line, individual periods this week, just the human, the competitor. I can't say enough about him.
"When he's out there laying down and he's reassuring me. That's who he is. He's reassuring me, and has a smile on his face, actually. He trusts God. He trusts himself. He trusts life. He's just one of those types of people. Tough to see that, obviously."
Hamilton is in the final season of a three-year, $34.5 million contract extension he signed in April 2023.
Murray has 15 tackles this season. He signed a three-year, $19.5 million contract in free agency with the Jaguars in 2025 after spending five seasons with Houston, one with Cleveland and three with Kansas City.
