ORCHARD PARK, N.Y. -- The Buffalo Bills are unlikely to have starting linebacker Nigel Bradham available Sunday when they host the Houston Texans in their first home game in nearly a month.

Bradham injured in ankle in Sunday's loss to the Kansas City Chiefs and was spotted in a walking boot in the locker room after the game. Coach Rex Ryan said Monday that Bradham has a high ankle sprain and that it "doesn't look great" for him to play against the Texans.

Defensive end Alex Carrington is likely to miss the remainder of the season with a leg injury suffered in the loss to Kansas City, Ryan said Monday. Carrington was making his first start of the season in place of Mario Williams, who has a foot injury. Ryan said Monday that he hopes Williams can play "in some capacity" against the Texans.

Running back Karlos Williams suffered a shoulder injury Sunday and his status for Sunday's game against Houston is still up the air, Ryan said Monday.

Guard John Miller (ankle) is not expected to play against Houston.