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Monday, September 14, 2026
Top 25 betting lines: Ole Miss favored at home against LSU in Kiffin's return

By ESPN

Ole Miss QB Trinidad Chambliss faces a huge test with LSU coming to town.

The college football season marches on in Week 3 with three ranked opponents facing one another, and no game is bigger than the one in Oxford, Miss. as Lane Kiffin and the No. 7 LSU�plays No. 8 Ole Miss. Kiffin went 55-19 in his six seasons as the head coach of the Rebels before leaving for LSU prior to the College Football Playoff.

Elsewhere, the No. 16 SMU�play at No. 23 Louisville, and No. 22 Houston�visits No. 13 Texas Tech.

No. 1 Texas�(vs. UTSA), No. 2 Georgia�(at Arkansas), No. 3 Notre Dame�(vs. Michigan State), No. 4 Indiana(vs. Western Kentucky) and No. 5 Miami�(at Wake Forest) are all favored by 20 points or more.

Here's a closer look at the lines for all the teams in the top 25.

All times Eastern.�Odds by DraftKings�and�subject to change.


No. 5 Miami -21.5 at Wake Forest

Friday, 7:30 p.m., ESPN

Records: Miami 2-0, 0-0 vs. AP Top 25; Wake Forest 2-0, 0-0 vs. AP Top 25

Opening Line: Miami -19.5, O/U 50.5

Money line: Miami (-2100); Wake Forest (+1100)

Over/Under: 55.5 (O -108, U -112)





FPI Projection Miami by 20.4 points with a 92% probability to win game outright


No. 22 Houston at No. 13 Texas Tech -7.5

Friday, 8 p.m., FOX

Records: Houston 2-0, 0-0 vs. AP Top 25; Texas Tech 2-0, 0-0 vs. AP Top 25



No line posted



FPI Projection Texas Tech by 9.7 points with a 76% probability to win game outright


Portland State at No. 21 Oregon

Friday, 10:30 p.m., BTN

Records: Portland State 0-3 (9th in Big Sky); Oregon 1-1, 0-0 vs. AP Top 25



No line posted



FPI Projection Oregon by 49.1 points with a >99% probability to win game outright


No. 2 Georgia -24.5 at Arkansas

Saturday, Noon, ABC

Records: Georgia 2-0, 0-0 vs. AP Top 25; Arkansas 1-1, 0-1 vs. AP Top 25

Line Movement Alert: Opened Georgia -17.5, O/U 52.5

Money line: Georgia (-4500); Arkansas (+1700)

Over/Under: 54.5 (O -110, U -110)





FPI Projection Georgia by 27.2 points with a 96% probability to win game outright


Kent State at No. 6 Ohio State -52.5

Saturday, Noon, FOX

Records: Kent State 1-1, 0-0 vs. AP Top 25; Ohio State 1-1, 0-1 vs. AP Top 25

Opening Line: Ohio State -52.5, O/U 56.5

Over/Under: 58.5 (O -115, U -105)





FPI Projection Ohio State by 56.5 points with a >99% probability to win game outright


Buffalo at No. 14 Penn State -38.5

Saturday, Noon, BTN

Records: Buffalo 1-1, 0-0 vs. AP Top 25; Penn State 2-0, 0-0 vs. AP Top 25

Opening Line: Penn State -39.5, O/U 48.5

Over/Under: 47.5 (O -105, U -115)





FPI Projection Penn State by 34.7 points with a 98% probability to win game outright


Kentucky at No. 9 Texas A&M -16.5

Saturday, 3:30 p.m., ESPN

Records: Kentucky 1-1, 0-1 vs. AP Top 25; Texas A&M 2-0, 0-0 vs. AP Top 25

Opening Line: Texas A&M -15.5, O/U 48.5

Money line: Kentucky (+575); Texas A&M (-850)

Over/Under: 49.5 (O -110, U -110)





FPI Projection Texas A&M by 22.8 points with a 94% probability to win game outright


Florida State at No. 10 Alabama -20.5

Saturday, 3:30 p.m., ABC

Records: Florida State 1-1, 0-1 vs. AP Top 25; Alabama 2-0, 0-0 vs. AP Top 25

Line Movement Alert: Opened Alabama -15.5, O/U 52.5

Money line: Florida State (+950); Alabama (-1650)

Over/Under: 49.5 (O -110, U -110)





FPI Projection Alabama by 17.7 points with a 89% probability to win game outright


No. 12 USC -24.5 at Rutgers

Saturday, 3:30 p.m., CBS

Records: USC 3-0, 0-0 vs. AP Top 25; Rutgers 0-2, 0-0 vs. AP Top 25

Opening Line: USC -24.5, O/U 57.5

Money line: USC (-2800); Rutgers (+1300)

Over/Under: 58.5 (O -108, U -112)





FPI Projection USC by 26.7 points with a 96% probability to win game outright


No. 16 SMU at No. 23 Louisville -1.5

Saturday, 3:30 p.m., ESPN2

Records: SMU 2-0, 0-0 vs. AP Top 25; Louisville 1-1, 0-1 vs. AP Top 25

Opening Line: Louisville -1.5, O/U 56.5

Over/Under: - (O -112, U -115)





FPI Projection Louisville by 1 points with a 53% probability to win game outright


Utah State at No. 17 Utah -28.5

Saturday, 3:30 p.m., FOX

Records: Utah State 0-2, 0-1 vs. AP Top 25; Utah 2-0, 0-0 vs. AP Top 25

Opening Line: Utah -27.5, O/U 57.5

Money line: Utah State (+2200); Utah (-8000)

Over/Under: 56.5 (O -115, U -105)





FPI Projection Utah by 25.1 points with a 95% probability to win game outright


UTEP at No. 19 Michigan -35.5

Saturday, 3:30 p.m., BTN

Records: UTEP 1-1, 0-1 vs. AP Top 25; Michigan 2-0, 1-0 vs. AP Top 25

Opening Line: Michigan -36.5, O/U 49.5

Over/Under: 48.5 (O -112, U -108)





FPI Projection Michigan by 36.9 points with a 99% probability to win game outright


Western Kentucky at No. 4 Indiana -44.5

Saturday, 4 p.m., Peacock

Records: Western Kentucky 0-2, 0-1 vs. AP Top 25; Indiana 2-0, 0-0 vs. AP Top 25

Opening Line: Indiana -44.5, O/U 59.5

Over/Under: 60.5 (O -110, U -110)





FPI Projection Indiana by 43.4 points with a >99% probability to win game outright


Northern Iowa at No. 18 Iowa

Saturday, 4 p.m., FS1

Records: Northern Iowa 1-1 (1st in MVFC); Iowa 2-0, 0-0 vs. AP Top 25



No line posted



FPI Projection Iowa by 31.3 points with a 98% probability to win game outright


Troy at No. 20 Missouri -27.5

Saturday, 7 p.m., SECN+

Records: Troy 2-0, 0-0 vs. AP Top 25; Missouri 2-0, 0-0 vs. AP Top 25

Opening Line: Missouri -27.5, O/U 49.5

Money line: Troy (+2000); Missouri (-6500)

Over/Under: 49.5 (O -112, U -108)





FPI Projection Missouri by 25.1 points with a 95% probability to win game outright


Michigan State at No. 3 Notre Dame -29.5

Saturday, 7:30 p.m., NBC

Records: Michigan State 2-0, 0-0 vs. AP Top 25; Notre Dame 2-0, 0-0 vs. AP Top 25

Opening Line: Notre Dame -29.5, O/U 53.5

Money line: Michigan State (+2200); Notre Dame (-8000)

Over/Under: 52.5 (O -105, U -115)





FPI Projection Notre Dame by 27.8 points with a 96% probability to win game outright


No. 7 LSU at No. 8 Ole Miss -3

Saturday, 7:30 p.m., ABC

Records: LSU 2-0, 0-0 vs. AP Top 25; Ole Miss 2-0, 1-0 vs. AP Top 25

Opening Line: Ole Miss -1.5, O/U 57.5

Money line: LSU (-155); Ole Miss (+130)

Over/Under: 58.5 (O -112, U -108)





FPI Projection LSU by 5.3 points with a 65% probability to win game outright


No. 11 BYU -17.5 at Colorado State

Saturday, 7:30 p.m., CBS

Records: BYU 2-0, 0-0 vs. AP Top 25; Colorado State 2-0, 0-0 vs. AP Top 25

Line Movement Alert: Opened BYU -21, O/U 52.5

Money line: BYU (-1000); Colorado State (+650)

Over/Under: 52.5 (O -108, U -112)





FPI Projection BYU by 19.6 points with a 91% probability to win game outright


New Mexico at No. 24 Oklahoma -22.5

Saturday, 7:30 p.m., ESPN2

Records: New Mexico 2-0, 0-0 vs. AP Top 25; Oklahoma 1-1, 0-0 vs. AP Top 25

Opening Line: Oklahoma -23.5, O/U 48.5

Money line: New Mexico (+1200); Oklahoma (-2400)

Over/Under: 47.5 (O -118, U -102)





FPI Projection Oklahoma by 18.5 points with a 90% probability to win game outright


West Virginia at No. 25 Virginia -10

Saturday, 7:30 p.m., ACC Network

Records: West Virginia 2-0, 0-0 vs. AP Top 25; Virginia 2-0, 0-0 vs. AP Top 25

Opening Line: Virginia -8.5, O/U 50.5

Money line: West Virginia (+310); Virginia (-395)

Over/Under: 53.5 (O -112, U -108)





FPI Projection Virginia by 14.2 points with a 84% probability to win game outright


Kennesaw State at No. 15 Tennessee -35.5

Saturday, 7:45 p.m., SEC Network

Records: Kennesaw State 1-1, 0-0 vs. AP Top 25; Tennessee 2-0, 0-0 vs. AP Top 25

Opening Line: Tennessee -34.5, O/U 59.5

Money line: Kennesaw State (+5000); Tennessee (-100000)

Over/Under: 60.5 (O -110, U -110)





FPI Projection Tennessee by 32.2 points with a 98% probability to win game outright


UTSA at No. 1 Texas -29.5

Saturday, 8 p.m., SECN+

Records: UTSA 2-0, 0-0 vs. AP Top 25; Texas 2-0, 1-0 vs. AP Top 25

Opening Line: Texas -29.5, O/U 57.5

Money line: UTSA (+2000); Texas (-6500)

Over/Under: 58.5 (O -105, U -115)





FPI Projection Texas by 37.6 points with a 99% probability to win game outright


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